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在科学排查时，我们可以说“大概率是假阳性”；但在细胞产品放行时，这种带有一点点瑕疵和严重环境污染背景的数据，就是一颗绝对不能放行的“定时炸弹”。

文献解析：生物信息学部分(9)-BayesPrism近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：Flowcytometry and pan-cancer TCGA data deconvoluted by BayesPrism (85), a Bayesianstatistical model that infers cell type comp...

文献解析：生物信息学部分(8)-CytoTRACE、scTour和Monocle3近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：To comparethe early and late differentiation stages of EF- and GC-derived ASCs, we usedthree methods to infer t...

文献解析：生物信息学部分(7)-CellPhoneDB和CellChat近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：CellPhoneDB and Cell-Chat were applied toidentify the potential receptor and ligand interaction between B cells ando...

文献解析：生物信息学部分(6)-SCENIC近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：We used SCENIC to predict and validate theTF regulatory network.1.      文献来源Ma J, Wu Y, Ma L, Yang X, Zhang T, Song G,Li T, Gao K,...

文献解析：生物信息学部分(5)- STARTRAC近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：BCR lineage tracing and overlap wascalculated by the Jaccard index and the STARTRAC package (v0.1.0).文献来源：1.      Ma J, Wu Y, M...

文献解析：生物信息学部分(3)- Change-O近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：TheChange-O repertoire clonal assignment toolkit was applied to defined clones,SHM, BCR clonal diversity, and abundances.文献来源：1...

文献解析：生物信息学部分(3)- Seurat算法近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：Harmony (v0.1.0) was applied for datasetintegration, and the matrix was used for clustering with the default Seuratpipeline. Ma...

文献解析：生物信息学部分(2)- Harmony算法       近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：We also integrated diverse published datasets containing TIBs, corrected the batch effects using the Harmony algorithm ...

文献解析：生物信息学部分(1)-DoubletFinder近期发表于Science上的科研论文《癌症免疫学-人类肿瘤浸润性B细胞的蓝图》文献中提到：We applied CellRanger V7 for read alignmentand gene-count matrix generation and BCR sequence assembly. Potential doubletswe...